BERND HEINRICH WILHELM VON KLEIST
\bˈɜːnd hˈe͡ɪnɹɪt͡ʃ wˈɪlhɛlm vˈɒn klˈɛst], \bˈɜːnd hˈeɪnɹɪtʃ wˈɪlhɛlm vˈɒn klˈɛst], \b_ˈɜː_n_d h_ˈeɪ_n_ɹ_ɪ_tʃ w_ˈɪ_l_h_ɛ_l_m v_ˈɒ_n k_l_ˈɛ_s_t]\
Definitions of BERND HEINRICH WILHELM VON KLEIST
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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