WERLHOFS DISEASE
\wˈɜːlhɒfs dɪzˈiːz], \wˈɜːlhɒfs dɪzˈiːz], \w_ˈɜː_l_h_ɒ_f_s d_ɪ_z_ˈiː_z]\
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Thrombocytopenia occurring in the absence of toxic exposure or a disease associated with decreased platelets. It is mediated by immune mechanisms, in most cases IMMUNOGLOBULIN G autoantibodies which attach to platelets and subsequently undergo destruction by macrophages. The disease is seen in acute (affecting children) and chronic (adult) forms.
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Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.