VENTRAL TEGMENTAL AREA
\vˈɛntɹə͡l tɛɡmˈɛntə͡l ˈe͡əɹi͡ə], \vˈɛntɹəl tɛɡmˈɛntəl ˈeəɹiə], \v_ˈɛ_n_t_ɹ_əl t_ɛ_ɡ_m_ˈɛ_n_t_əl ˈeə_ɹ_iə]\
Definitions of VENTRAL TEGMENTAL AREA
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A region in the mesencephalon which is dorsomedial to the substantia nigra and ventral to the red nucleus. The mesocortical and mesolimbic dopaminergic systems originate here, including an important projection to the nucleus accumbens. Overactivity of the cells in this area has been suspected to contribute to the positive symptoms of schizophrenia.
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- A clinical syndrome characterized by development of CHEST PAIN at rest concomitant transient ST segment elevation in the electrocardiogram, but with preserved exercise capacity.