UNREFRESHING

\ˌʌnɹɪfɹˈɛʃɪŋ], \ˌʌnɹɪfɹˈɛʃɪŋ], \ˌʌ_n_ɹ_ɪ_f_ɹ_ˈɛ_ʃ_ɪ_ŋ]\
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1874 - Etymological and pronouncing dictionary of the English language
By Stormonth, James, Phelp, P. H.

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MEN IIa

  • type multiple endocrine neoplasia characterized by virtually 100% incidence medullary thyroid carcinoma, a 50% pheochromocytoma, and lesser adenomas associated hyperparathyroidism. condition always transmitted through autosomal dominant inheritance. Genetic testing can identify individuals with the trait in early infancy. Treatment is usually excision of enlarged parathyroid glands. (From Holland et al., Cancer Medicine, 3d ed, pp1172-75)
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