TUMOR XENOGRAFT ASSAY
\tjˈuːmə zˈɛnəɡɹˌaft ɐsˈe͡ɪ], \tjˈuːmə zˈɛnəɡɹˌaft ɐsˈeɪ], \t_j_ˈuː_m_ə z_ˈɛ_n_ə_ɡ_ɹ_ˌa_f_t ɐ_s_ˈeɪ]\
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In vivo methods of screening investigative anticancer drugs, biologic response modifiers or radiotherapies. Human tumor tissue or cells are transplanted into mice or rats followed by tumor treatment regimens. A variety of outcomes are monitored to assess antitumor effectivness.
By DataStellar Co., Ltd
Word of the day
Procollagen Proline Dioxygenase
- mixed-function oxygenase that catalyzes hydroxylation prolyl-glycyl-containing-peptide, usually in protocollagen, hydroxyprolylglycyl-peptide. The enzyme utilizes molecular oxygen with a concomitant oxidative decarboxylation of 2-oxoglutarate to succinate. EC 1.14.11.2.