TUBERCULOSIS CUTIS INDURATIVA
\tjˌuːbəkjʊlˈə͡ʊsɪs kjˈuːtiz ɪndjˈʊ͡əɹɐtˌɪvə], \tjˌuːbəkjʊlˈəʊsɪs kjˈuːtiz ɪndjˈʊəɹɐtˌɪvə], \t_j_ˌuː_b_ə_k_j_ʊ_l_ˈəʊ_s_ɪ_s k_j_ˈuː_t_i_z ɪ_n_d_j_ˈʊə_ɹ_ɐ_t_ˌɪ_v_ə]\
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A type of panniculitis characterized histologically by the presence of granulomas, vasculitis, and necrosis. It is traditionally considered to be the tuberculous counterpart of nodular vasculitis, but is now known to occur without tuberculous precedent. It is seen most commonly in adolescent and menopausal women, is initiated or exacerbated by cold weather, and typically presents as one or more recurrent erythrocyanotic nodules or plaques on the calves. The nodules may progress to form indurations, ulcerations, and scars.
By DataStellar Co., Ltd
Word of the day
Procollagen Proline Dioxygenase
- mixed-function oxygenase that catalyzes hydroxylation prolyl-glycyl-containing-peptide, usually in protocollagen, hydroxyprolylglycyl-peptide. The enzyme utilizes molecular oxygen with a concomitant oxidative decarboxylation of 2-oxoglutarate to succinate. EC 1.14.11.2.