TRYPSIN INHIBITOR, ALPHA 1 ANTITRYPSIN
\tɹˈɪpsɪn ɪnhˈɪbɪtə], \tɹˈɪpsɪn ɪnhˈɪbɪtə], \t_ɹ_ˈɪ_p_s_ɪ_n ɪ_n_h_ˈɪ_b_ɪ_t_ə]\
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Plasma glycoprotein member of the serpin superfamily which inhibits trypsin, neutrophil elastase, and other proteolytic enzymes. Commonly referred to as alpha 1-proteinase inhibitor (A1PI), it exists in over 30 different biochemical variant forms known collectively as the Pi (protease inhibitor) system. Hereditary A1PI deficiency is associated with pulmonary emphysema.
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Procollagen Proline Dioxygenase
- mixed-function oxygenase that catalyzes hydroxylation prolyl-glycyl-containing-peptide, usually in protocollagen, hydroxyprolylglycyl-peptide. The enzyme utilizes molecular oxygen with a concomitant oxidative decarboxylation of 2-oxoglutarate to succinate. EC 1.14.11.2.