TRANSPORT PIECE
\tɹˈanspɔːt pˈiːs], \tɹˈanspɔːt pˈiːs], \t_ɹ_ˈa_n_s_p_ɔː_t p_ˈiː_s]\
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A glycoprotein found in a variety of external secretions (tears, bile, colostrum) usually complexed to secreted polymeric immunoglobulins (IMMUNOGLOBULIN A or, less frequently IMMUNOGLOBULIN M). It is derived, by proteolytic cleavage, from the polymeric immunoglobulin receptor (RECEPTORS, POLYMERIC IMMUNOGLOBULIN) and probably functions to protect the immunoglobulins from proteolysis in the secretions. (From Rosen et al., The Dictionary of Immunology, 1989)
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Word of the day
Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.