TRANSFORMED CELL LINE
\tɹansfˈɔːmd sˈɛl lˈa͡ɪn], \tɹansfˈɔːmd sˈɛl lˈaɪn], \t_ɹ_a_n_s_f_ˈɔː_m_d s_ˈɛ_l l_ˈaɪ_n]\
Sort: Oldest first
-
Eukaryotic cell line obtained in a quiescent or stationary phase which undergoes conversion to a state of unregulated growth in culture, resembling an in vitro tumor. It occurs spontaneously or through interaction with viruses, oncogenes, radiation, or drugs/chemicals.
By DataStellar Co., Ltd
Word of the day
Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.