TOXIN CONJUGATE
\tˈɒksɪn kˈɒnd͡ʒuːɡˌe͡ɪt], \tˈɒksɪn kˈɒndʒuːɡˌeɪt], \t_ˈɒ_k_s_ɪ_n k_ˈɒ_n_dʒ_uː_ɡ_ˌeɪ_t]\
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Semisynthetic conjugates of various toxic molecules, including radioactive isotopes and bacterial or plant toxins, with specific immune substances such as immunoglobulins, monoclonal antibodies, and antigens. The antitumor or antiviral immune substance carries the toxin to the tumor or infected cell where the toxin exerts its poisonous effect.
By DataStellar Co., Ltd
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.