TONIC CLONIC CONVULSIONS
\tˈɒnɪk klˈɒnɪk kənvˈʌlʃənz], \tˈɒnɪk klˈɒnɪk kənvˈʌlʃənz], \t_ˈɒ_n_ɪ_k k_l_ˈɒ_n_ɪ_k k_ə_n_v_ˈʌ_l_ʃ_ə_n_z]\
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A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process). (From Adams et al., Principles of Neurology, 6th ed, p329)
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.
Nearby Words
- tonic clonic convulsion
- tonic clonic convulsion disorder
- tonic clonic convulsion disorders
- tonic clonic convulsion syndrome
- tonic clonic convulsion syndromes
- Tonic Clonic Convulsions
- tonic clonic epilepsies
- tonic clonic epilepsy
- tonic clonic seizure
- tonic clonic seizure disorder
- tonic clonic seizure disorders