\tˈɪmp wˈɒn], \tˈɪmp wˈɒn], \t_ˈɪ_m_p w_ˈɒ_n]\
Definitions of TIMP 1
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A member of the family of TISSUE INHIBITOR OF METALLOPROTEINASES. It is a N-glycosylated protein, molecular weight 28 kD, produced by a vast range of cell types and found in a variety of tissues and body fluids. It has been shown to suppress metastasis and inhibit tumor invasion in vitro.
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Idiopathic Hypercatabolic Hypoproteinemias
- series of gastrointestinal disorders which share in common excessive loss protein, mainly albumin, across gut wall. occur stomach (Menetrier disease), as well the small bowel (intestinal lymphangiectases, assorted inflammatory states). They are also occasionally associated with congestive heart failure (again a bowel protein loss).