THIENAMYCINS
\θˈi͡ənɐmˌɪsɪnz], \θˈiənɐmˌɪsɪnz], \θ_ˈiə_n_ɐ_m_ˌɪ_s_ɪ_n_z]\
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Beta-lactam antibiotics that differ from PENICILLINS in having the thiazolidine sulfur atom replaced by carbon, the sulfur then becoming the first atom in the side chain. They are unstable chemically, but have a very broad antibacterial spectrum. Thienamycin and its more stable derivatives are proposed for use in combinations with enzyme inhibitors.
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