TETRAHYDROFOLATE DEHYDROGENASE
\tˈɛtɹɑːɹˌa͡ɪdɹəfˌɒle͡ɪt dˌiːha͡ɪdɹˈə͡ʊd͡ʒne͡ɪs], \tˈɛtɹɑːɹˌaɪdɹəfˌɒleɪt dˌiːhaɪdɹˈəʊdʒneɪs], \t_ˈɛ_t_ɹ_ɑː_ɹ_ˌaɪ_d_ɹ_ə_f_ˌɒ_l_eɪ_t d_ˌiː_h_aɪ_d_ɹ_ˈəʊ_dʒ_n_eɪ_s]\
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An enzyme of the oxidoreductase class that catalyzes the reaction 7,8-dihyrofolate and NADPH to yield 5,6,7,8-tetrahydrofolate and NADPH+, producing reduced folate for amino acid metabolism, purine ring synthesis, and the formation of deoxythymidine monophosphate. Methotrexate and other folic acid antagonists used as chemotherapeutic drugs act by inhibiting this enzyme. (Dorland, 27th ed) EC 1.5.1.3.
By DataStellar Co., Ltd
Nearby Words
- tetrahydrocannabinol
- tetrahydrocannabinol, (6a trans) isomer
- tetrahydrocannabinol, (6ar cis) isomer
- tetrahydrocannabinol, (6as cis) isomer
- tetrahydrocannabinol, trans (+ ) isomer
- Tetrahydrofolate Dehydrogenase
- tetrahydrofolate formylase
- tetrahydrolinoleic acids
- tetrahydronaphthalenes
- tetrahydropapaveroline
- tetrahydroparaquinanisol