TETANUS TOXIN
\tˈɛtənəs tˈɒksɪn], \tˈɛtənəs tˈɒksɪn], \t_ˈɛ_t_ə_n_ə_s t_ˈɒ_k_s_ɪ_n]\
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The toxin elaborated by Clostridium tetani. It is a protein with a molecular weight of about 150,000, probably consisting of two fragments, tetanolysin being the hemolytic and tetanospasmin the neurotoxic principle. The toxin causes disruption of the inhibitory mechanisms of the CNS, thus permitting uncontrolled nervous activity, leading to fatal convulsions.
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