TERMINAL ADDITION ENZYME
\tˈɜːmɪnə͡l ɐdˈɪʃən ˈɛnza͡ɪm], \tˈɜːmɪnəl ɐdˈɪʃən ˈɛnzaɪm], \t_ˈɜː_m_ɪ_n_əl ɐ_d_ˈɪ_ʃ_ə_n ˈɛ_n_z_aɪ_m]\
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A non-template-directed DNA polymerase normally found in vertebrate thymus and bone marrow. It catalyzes the elongation of oligo- or polydeoxynucleotide chains and is widely used as a tool in the differential diagnosis of acute leukemias in man. EC 2.7.7.31.
By DataStellar Co., Ltd
Word of the day
Procollagen Proline Dioxygenase
- mixed-function oxygenase that catalyzes hydroxylation prolyl-glycyl-containing-peptide, usually in protocollagen, hydroxyprolylglycyl-peptide. The enzyme utilizes molecular oxygen with a concomitant oxidative decarboxylation of 2-oxoglutarate to succinate. EC 1.14.11.2.