\tɛmd͡ʒˈiːzɪk], \tɛmdʒˈiːzɪk], \t_ɛ_m_dʒ_ˈiː_z_ɪ_k]\
Definitions of TEMGESIC
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A derivative of the opioid alkaloid THEBAINE that is a more potent and longer lasting analgesic than MORPHINE. It appears to act as a partial agonist at mu and kappa opioid receptors and as an antagonist at delta receptors. The lack of delta-agonist activity has been suggested to account for the observation that buprenorphine tolerance may not develop with chronic use.
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