TAC P55 PEPTIDE
\tˈak pˈiː fˈɪftifˈa͡ɪv pˈɛpta͡ɪd], \tˈak pˈiː fˈɪftifˈaɪv pˈɛptaɪd], \t_ˈa_k p_ˈiː f_ˈɪ_f_t_i_f_ˈaɪ_v p_ˈɛ_p_t_aɪ_d]\
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Receptors present on activated T- and B-cells as a complex consisting of a 55 kD peptide, which reacts with the anti-Tac monoclonal antibody, and a 75 kD non-Tac interleukin-2-binding peptide. The receptor is present in two forms, one with a very high affinity and the other with low affinity for IL-2. The high-affinity form appears to mediate exclusively the growth-promoting response to IL-2. The receptor is present in large numbers on resting HUMAN T-LYMPHOTROPIC VIRUS 1 leukemia cells, but not on normal resting cells.
By DataStellar Co., Ltd
