SV40 T ANTIGENS
\ˌɛsvˈiː fˈɔːti tˈiː ˈantɪd͡ʒˌɛnz], \ˌɛsvˈiː fˈɔːti tˈiː ˈantɪdʒˌɛnz], \ˌɛ_s_v_ˈiː f_ˈɔː_t_i t_ˈiː_ ˈa_n_t_ɪ_dʒ_ˌɛ_n_z]\
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Polyomavirus antigens which cause infection and cellular transformation. The large T antigen is necessary for the initiation of viral DNA synthesis, repression of transcription of the early region and is responsible in conjunction with the middle T antigen for the transformation of primary cells. Small T antigen is necessary for the completion of the productive infection cycle.
By DataStellar Co., Ltd
