SURFACE CD4 RECEPTOR
\sˈɜːfɪs sˌiːdˈiː fˈɔː ɹɪsˈɛptə], \sˈɜːfɪs sˌiːdˈiː fˈɔː ɹɪsˈɛptə], \s_ˈɜː_f_ɪ_s s_ˌiː_d_ˈiː f_ˈɔː ɹ_ɪ_s_ˈɛ_p_t_ə]\
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55-kD Glycoproteins originally defined as differentiation antigens on T-lymphocytes, but also found on other cells including monocytes/macrophages. CD4 antigens are members of the immunoglobulin supergene family and are implicated as associative recognition elements in MHC (Major Histocompatibility Complex) Class II-restricted immune responses. On T-lymphocytes they define the helper/inducer subset. CD4 antigens also serve as HIV receptors, binding directly to the envelope protein gp120 on HIV.
By DataStellar Co., Ltd
