SPINDLE CELL NEVUS
\spˈɪndə͡l sˈɛl nˈɛvəs], \spˈɪndəl sˈɛl nˈɛvəs], \s_p_ˈɪ_n_d_əl s_ˈɛ_l n_ˈɛ_v_ə_s]\
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A form of pigmented nevus showing intense melanocytic activity around the dermo-epidermal junction. Large numbers of spindle-shaped melanocytes proliferate downward toward the dermis and usually a large amount of pigment is present. It was first described in 1976 and the bulk of patients reported have been young females with the lesions presenting on the thighs. (From Rook et al., Textbook of Dermatology, 4th ed, 1992, p185)
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Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.