SP1 TRANSCRIPTION FACTOR
\ˌɛspˈiː wˈɒn tɹanskɹˈɪpʃən fˈaktə], \ˌɛspˈiː wˈɒn tɹanskɹˈɪpʃən fˈaktə], \ˌɛ_s_p_ˈiː w_ˈɒ_n t_ɹ_a_n_s_k_ɹ_ˈɪ_p_ʃ_ə_n f_ˈa_k_t_ə]\
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Promoter-specific RNA polymerase II transcription factor that binds to the GC box, one of the upstream promoter elements (UPE) in mammalian cells. The binding of Sp1 is necessary to initiate transcription in the promoters of a variety of cellular and viral genes including c-Ha-ras and HIV.
By DataStellar Co., Ltd
