SIGNIFICATIVELY

\sˈɪɡnɪfˌɪkətˌɪvli], \sˈɪɡnɪfˌɪkətˌɪvli], \s_ˈɪ_ɡ_n_ɪ_f_ˌɪ_k_ə_t_ˌɪ_v_l_i]\
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1914 - Nuttall's Standard dictionary of the English language
By Nuttall, P.Austin.