RWJ15927
\ˌɑːdˌʌbə͡ljˌuːd͡ʒˈe͡ɪ fˈɪftiːn θˈa͡ʊzənd nˈa͡ɪnhˈʌndɹədən twˈɛntisˈɛvən], \ˌɑːdˌʌbəljˌuːdʒˈeɪ fˈɪftiːn θˈaʊzənd nˈaɪnhˈʌndɹədən twˈɛntisˈɛvən], \ˌɑː_d_ˌʌ_b_əl_j_ˌuː_dʒ_ˈeɪ f_ˈɪ_f_t_iː_n θ_ˈaʊ_z_ə_n_d_ n_ˈaɪ_n_h_ˈʌ_n_d_ɹ_ə_d_ə_n t_w_ˈɛ_n_t_i_s_ˈɛ_v_ə_n]\
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A synthetic methylprostaglandin E1 analog that reduces gastric acid secretion and enhances the gastric mucus-bicarbonate barrier. It is effective in the therapy of gastric ulcers and gives significant protection against NSAID-induced gastric mucosal damage. The drug also prevents cyclosporin A-induced damage to endocrine and exocrine pancreatic secretions. It shows a low order of acute toxicity and there is no evidence of embryotoxicity, fetotoxicity, teratogenicity, or mutagenicity in animal studies.
By DataStellar Co., Ltd