ROUSSY LEVY SYNDROME
\ɹˈa͡ʊsi lˈɛvi sˈɪndɹə͡ʊm], \ɹˈaʊsi lˈɛvi sˈɪndɹəʊm], \ɹ_ˈaʊ_s_i l_ˈɛ_v_i s_ˈɪ_n_d_ɹ_əʊ_m]\
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A hereditary motor and sensory neuropathy transmitted most often as an autosomal dominant trait and characterized by progressive distal wasting and loss of reflexes in the muscles of the legs (and occasionally involving the arms). Onset is usually in the second to fourth decade of life. This condition has been divided into two subtypes, hereditary motor and sensory neuropathy (HMSN) types I and II. HMSN I is associated with abnormal nerve conduction velocities and nerve hypertrophy, features not seen in HMSN II. (Adams et al., Principles of Neurology, 6th ed, p1343)
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Word of the day
Harmar, Josiah
- (1753-1813), born in Philadelphia, served during Revolutionary War, attaining rank of lieutenant-colonel, and was commander-in-chief the U.S. army from 1789 to 1792.
Nearby Words
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