RETINOBLASTOMA NUCLEAR PHOSPHOPROTEIN P105 RB
\ɹˌɛtɪnˌə͡ʊblastˈə͡ʊmə njˈuːkli͡ə fˈɒsfəpɹˌə͡ʊtiːn pˈiː wˈɒnhˈʌndɹədən fˈa͡ɪv ˌɑːbˈiː], \ɹˌɛtɪnˌəʊblastˈəʊmə njˈuːkliə fˈɒsfəpɹˌəʊtiːn pˈiː wˈɒnhˈʌndɹədən fˈaɪv ˌɑːbˈiː], \ɹ_ˌɛ_t_ɪ_n_ˌəʊ_b_l_a_s_t_ˈəʊ_m_ə n_j_ˈuː_k_l_iə f_ˈɒ_s_f_ə_p_ɹ_ˌəʊ_t_iː_n p_ˈiː w_ˈɒ_n_h_ˈʌ_n_d_ɹ_ə_d_ə_n f_ˈaɪ_v ˌɑː_b_ˈiː]\
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Product of the retinoblastoma tumor suppressor gene. It is a nuclear phosphoprotein hypothesized to normally act as an inhibitor of cell proliferation. Rb protein is absent in retinoblastoma cell lines. It also has been shown to form complexes with the adenovirus E1A protein, the SV40 T antigen, and the human papilloma virus E7 protein.
By DataStellar Co., Ltd
Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.
Nearby Words
- retinitis pigmentosa
- retinitis syphilitica
- retinoblastoma
- retinoblastoma gene
- retinoblastoma genes
- Retinoblastoma Nuclear Phosphoprotein p105 Rb
- retinoblastoma protein
- retinoblastomas
- retinochorioiditis, retinochoroiditis
- retinochoroiditis
- retinoic acid