PROVOCHOLINE
\pɹəvˈɒkəlˌiːn], \pɹəvˈɒkəlˌiːn], \p_ɹ_ə_v_ˈɒ_k_ə_l_ˌiː_n]\
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A quarternary ammonium parasympathomimetic agent with the muscarinic actions of ACETYLCHOLINE. It is hydrolysed by ACETYLCHOLINESTERASE at a considerably slower rate than ACETYLCHOLINE and is more resistant to hydrolysis by nonspecific CHOLINESTERASES so that its actions are more prolonged. It is used as a parasympathomimetic bronchoconstrictor agent and as a diagnostic aid for bronchial asthma. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1116)
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