PROTO ONCOGENE PRODUCTS C JUN
\pɹˈə͡ʊtə͡ʊ ˈɒnkə͡ʊd͡ʒˌiːn pɹˈɒdʌkts sˈiː d͡ʒˈʌn], \pɹˈəʊtəʊ ˈɒnkəʊdʒˌiːn pɹˈɒdʌkts sˈiː dʒˈʌn], \p_ɹ_ˈəʊ_t_əʊ ˈɒ_n_k_əʊ_dʒ_ˌiː_n p_ɹ_ˈɒ_d_ʌ_k_t_s s_ˈiː dʒ_ˈʌ_n]\
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Cellular DNA-binding proteins encoded by the c-jun genes (GENES, JUN). They are involved in growth-related transcriptional control. There appear to be three distinct functions: dimerization (with c-fos), DNA-binding, and transcriptional activation. Oncogenic transformation can take place by constitutive expression of c-jun.
By DataStellar Co., Ltd
