PLURONIC L101
\plʊ͡əɹˈɒnɪk ˈɛl wˈɒnhˈʌndɹədən wˈɒn], \plʊəɹˈɒnɪk ˈɛl wˈɒnhˈʌndɹədən wˈɒn], \p_l_ʊə_ɹ_ˈɒ_n_ɪ_k ˈɛ_l w_ˈɒ_n_h_ˈʌ_n_d_ɹ_ə_d_ə_n w_ˈɒ_n]\
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A nonionic polyoxyethylene-polyoxypropylene block co-polymer with the general formula HO (C2H4O)a (-C3H6O)b (C2H4O)aH. It is available in different grades which vary from liquids to solids. It is used as an emulsifying agent, solubilising agent, surfactant, and wetting agent for antibiotics. Poloxamer is also used in ointment and suppository bases and as a tablet binder or coater. (Martindale The Extra Pharmacopoeia, 31st ed)
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Procollagen Proline Dioxygenase
- mixed-function oxygenase that catalyzes hydroxylation prolyl-glycyl-containing-peptide, usually in protocollagen, hydroxyprolylglycyl-peptide. The enzyme utilizes molecular oxygen with a concomitant oxidative decarboxylation of 2-oxoglutarate to succinate. EC 1.14.11.2.