PLEOMORPHIC LIPOSARCOMAS
\plɪəmˈɔːfɪk lˌɪpəsɑːkˈə͡ʊməz], \plɪəmˈɔːfɪk lˌɪpəsɑːkˈəʊməz], \p_l_ɪ__ə_m_ˈɔː_f_ɪ_k l_ˌɪ_p_ə_s_ɑː_k_ˈəʊ_m_ə_z]\
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A malignant tumor derived from primitive or embryonal lipoblastic cells. It may be composed of well-differentiated fat cells or may be dedifferentiated: myxoid (LIPOSARCOMA, MYXOID), round-celled, or pleomorphic, usually in association with a rich network of capillaries. Recurrences are common and dedifferentiated liposarcomas metastasize to the lungs or serosal surfaces. (From Dorland, 27th ed; Stedman, 25th ed)
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Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.