PLATINUM DIAMMINODICHLORIDE
\plˈatɪnəm dˈa͡ɪəmˌɪnədˌɪklɔːɹˌa͡ɪd], \plˈatɪnəm dˈaɪəmˌɪnədˌɪklɔːɹˌaɪd], \p_l_ˈa_t_ɪ_n_ə_m d_ˈaɪ_ə_m_ˌɪ_n_ə_d_ˌɪ_k_l_ɔː_ɹ_ˌaɪ_d]\
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An inorganic and water-soluble platinum complex. After undergoing hydrolysis, it reacts with DNA to produce both intra and interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity of cisplatin correlates with cellular arrest in the G2 phase of the cell cycle.
By DataStellar Co., Ltd
Nearby Words
- platinotype
- platinous
- platinum
- platinum black
- platinum compounds
- Platinum Diamminodichloride
- platinum group
- platinum thermometer
- platinum-blonde
- platitude
- platitudes