\fˈɪlɪp hˈɛnɹi ɡˈə͡ʊp], \fˈɪlɪp hˈɛnɹi ɡˈə‍ʊp], \f_ˈɪ_l_ɪ_p h_ˈɛ_n_ɹ_i ɡ_ˈəʊ_p]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Proto Oncogene Proteins c erbB 2

  • cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.
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