PARALYSIS, PERIODIC, HYPERKALEMIC, FAMILIAL
\pəɹˈaləsˌɪs], \pəɹˈaləsˌɪs], \p_ə_ɹ_ˈa_l_ə_s_ˌɪ_s]\
Definitions of PARALYSIS, PERIODIC, HYPERKALEMIC, FAMILIAL
Sort: Oldest first
An autosomal dominant familial disorder which presents in infancy or childhood and is characterized by episodes of weakness associated with hyperkalemia. During attacks, muscles of the lower extremities are initially affected, followed by the lower trunk and arms. Episodes last from 15-60 minutes and typically occur after a period of rest following exercise. A defect in skeletal muscle sodium channels has been identified as the cause of this condition. Normokalemic periodic paralysis is a closely related disorder marked by a lack of alterations in potassium levels during attacks of weakness. (Adams et al., Principles of Neurology, 6th ed, p1481)
By DataStellar Co., Ltd
Word of the day
- A Brazilian beetle, resembling in the male pair of pincers.