PANCREAS FIBROCYSTIC DISEASES
\pˈankɹi͡əs fˌɪbɹəsˈɪstɪk dɪzˈiːzɪz], \pˈankɹiəs fˌɪbɹəsˈɪstɪk dɪzˈiːzɪz], \p_ˈa_n_k_ɹ_iə_s f_ˌɪ_b_ɹ_ə_s_ˈɪ_s_t_ɪ_k d_ɪ_z_ˈiː_z_ɪ_z]\
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An inherited disease of exocrine glands, affecting most characteristically the pancreas, respiratory system, and sweat glands, usually beginning in infancy and typified by chronic respiratory infections, pancreatic insufficiency, and susceptibility to heat prostration. Cirrhosis of liver occurring in childhood is common and may produce portal hypertension, splenomegaly, and hypersplenism.
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Word of the day
Procollagen Proline Dioxygenase
- mixed-function oxygenase that catalyzes hydroxylation prolyl-glycyl-containing-peptide, usually in protocollagen, hydroxyprolylglycyl-peptide. The enzyme utilizes molecular oxygen with a concomitant oxidative decarboxylation of 2-oxoglutarate to succinate. EC 1.14.11.2.