\ˈɒksɪdətˌɪv bˈɜːsts], \ˈɒksɪdətˌɪv bˈɜːsts], \ˈɒ_k_s_ɪ_d_ə_t_ˌɪ_v b_ˈɜː_s_t_s]\
Definitions of OXIDATIVE BURSTS
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A large increase in oxygen uptake by neutrophils and most types of tissue macrophages through activation of an NADPH-cytochrome b-dependent oxidase that reduces oxygen to a superoxide. Individuals with an inherited defect in which the oxidase that reduces oxygen to superoxide is decreased or absent (GRANULOMATOUS DISEASE, CHRONIC) often die as a result of recurrent bacterial infections.
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