NEUROMUSCULAR BLOCK
\njˌuːɹəmˈʌskjʊlə blˈɒk], \njˌuːɹəmˈʌskjʊlə blˈɒk], \n_j_ˌuː_ɹ_ə_m_ˈʌ_s_k_j_ʊ_l_ə b_l_ˈɒ_k]\
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The intentional interruption of transmission at the NEUROMUSCULAR JUNCTION by external agents, usually neuromuscular blocking agents. It is distinguished from NERVE BLOCK in which nerve conduction (NEURAL CONDUCTION) is interrupted rather than neuromuscular transmission. Neuromuscular blockade is commonly used to produce MUSCLE RELAXATION as an adjunct to anesthesia during surgery and other medical procedures. It is also often used as an experimental manipulation in basic research. It is not strictly speaking anesthesia but is grouped here with anesthetic techniques. The failure of neuromuscular transmission as a result of pathological processes is not included here.
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