NEUROGLIA
\njuːɹˈɒɡli͡ə], \njuːɹˈɒɡliə], \n_j_uː_ɹ_ˈɒ_ɡ_l_iə]\
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The non-neuronal cells of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu, participate in the BLOOD-BRAIN BARRIER and BLOOD-RETINAL BARRIER, form the myelin insulation of nervous pathways, guide neuronal migration during development, and exchange metabolites with neurons. Neuroglia have high-affinity transmitter uptake systems, voltage-dependent and transmitter-gated ion channels, and can release transmitters, but their role in signaling (as in many other functions) is unclear.
By DataStellar Co., Ltd
By William R. Warner
By Willam Alexander Newman Dorland
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Colony Stimulating Factor 1
- mononuclear phagocyte factor (CSF) synthesized by mesenchymal cells. The compound stimulates survival, proliferation, and differentiation hematopoietic cells monocyte-series. M-CSF is a disulfide-bonded glycoprotein dimer with MW of 70 kDa. It binds to specific high affinity receptor (RECEPTOR, MACROPHAGE COLONY-STIMULATING FACTOR).