NEUROFIBROMAS
\njˌuːɹəfɪbɹˈə͡ʊməz], \njˌuːɹəfɪbɹˈəʊməz], \n_j_ˌuː_ɹ_ə_f_ɪ_b_ɹ_ˈəʊ_m_ə_z]\
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A moderately firm, benign, encapsulated tumor resulting from proliferation of SCHWANN CELLS and FIBROBLASTS that includes portions of nerve fibers. The tumors usually develop along peripheral or cranial nerves and are a central feature of NEUROFIBROMATOSIS 1, where they may occur intracranially or involve spinal roots. Pathologic features include fusiform enlargement of the involved nerve. Microscopic examination reveals a disorganized and loose cellular pattern with elongated nuclei intermixed with fibrous strands. (From Adams et al., Principles of Neurology, 6th ed, p1016)
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Snake's-head
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