NAKED DNA VACCINES
\nˈe͡ɪkɪd dˌiːˌɛnˈe͡ɪ vaksˈiːnz], \nˈeɪkɪd dˌiːˌɛnˈeɪ vaksˈiːnz], \n_ˈeɪ_k_ɪ_d d_ˌiː__ˌɛ_n_ˈeɪ v_a_k_s_ˈiː_n_z]\
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Recombinant DNA vectors encoding antigens administered for the prevention or treatment of disease. The host cells take up the DNA, express the antigen, and present it to the immune system in a manner similar to that which would occur during natural infection. This induces humoral and cellular immune responses against the encoded antigens. The vector is called naked DNA because there is no need for complex formulations or delivery agents; the plasmid is injected in saline or other buffers.
By DataStellar Co., Ltd
