MYOCARDIAL REPERFUSION INJURY
\mˌa͡ɪəkˈɑːdɪəl ɹɪpəfjˈuːʒən ˈɪnd͡ʒəɹi], \mˌaɪəkˈɑːdɪəl ɹɪpəfjˈuːʒən ˈɪndʒəɹi], \m_ˌaɪ_ə_k_ˈɑː_d_ɪ__ə_l ɹ_ɪ_p_ə_f_j_ˈuː_ʒ_ə_n ˈɪ_n_dʒ_ə_ɹ_i]\
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Functional, metabolic, or structural changes in ischemic heart muscle thought to result from REPERFUSION to the ischemic areas. Changes can be fatal to muscle cells and may include edema with explosive cell swelling and disintegration, sarcolemma disruption, fragmentation of mitochondria, contraction band necrosis, enzyme washout, and calcium overload. Other damage may include hemorrhage and ventricular arrhythmias. One possible mechanism of damage is thought to be oxygen free radicals. Treatment currently includes the introduction of scavengers of oxygen free radicals, and injury is thought to be prevented by warm blood cardioplegic infusion prior to reperfusion.
By DataStellar Co., Ltd
Nearby Words
- myocardial preconditioning
- myocardial preinfarction syndrome
- myocardial preinfarction syndromes
- myocardial reperfusion
- myocardial reperfusion injuries
- Myocardial Reperfusion Injury
- myocardial reperfusions
- myocardial revascularization
- myocardial revascularizations
- myocardial stimulants
- myocardial stunning