MYELOID METAPLASIA
\mˈa͡ɪɪlˌɔ͡ɪd mˌɛtəplˈe͡ɪzi͡ə], \mˈaɪɪlˌɔɪd mˌɛtəplˈeɪziə], \m_ˈaɪ_ɪ_l_ˌɔɪ_d m_ˌɛ_t_ə_p_l_ˈeɪ_z_iə]\
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The occurrence of myeloid tissue in extramedullary sites. Specifically it is a syndrome characterized by splenomegaly, anemia, the presence of nucleated erythrocytes and immature granulocytes in the circulating blood, and extramedullary hemoatopoiesis in the liver and spleen. The primary form is also known as agnogenic myeloid metaplasia, myelosclerosis, and myelofibrosis. The secondary or symptomatic form may be associated with various diseases, including carcinomatosis, tuberculosis, leukemia, and polycythemia vera. (Dorland, 27th ed)
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Photofrin II
- purified component HEMATOPORPHYRIN DERIVATIVE, consists a mixture oligomeric porphyrins. used therapy (PHOTORADIATION); treat malignant lesions with visible light and experimentally as an antiviral agent. It is the first drug to be approved in use of photodynamic therapy United States.