MYALGIC ENCEPHALOMYELITIS
\ma͡ɪˈald͡ʒɪk ɛnsˌɛfɐlˌɒmɪɪlˈa͡ɪtɪs], \maɪˈaldʒɪk ɛnsˌɛfɐlˌɒmɪɪlˈaɪtɪs], \m_aɪ__ˈa_l_dʒ_ɪ_k ɛ_n_s_ˌɛ_f_ɐ_l_ˌɒ_m_ɪ__ɪ_l_ˈaɪ_t_ɪ_s]\
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A syndrome characterized by persistent or recurrent fatigue, diffuse musculoskeletal pain, sleep disturbances, and subjective cognitive impairment of 6 months duration or longer. Symptoms are not caused by ongoing exertion; are not relieved by rest; and result in a substantial reduction of previous levels of occupational, educational, social, or personal activities. Minor alterations of immune, neuroendocrine, and autonomic function may be associated with this syndrome. There is also considerable overlap between this condition and FIBROMYALGIA. (From Semin Neurol 1998;18 (2):237-42; Ann Intern Med 1994 Dec 15;121 (12): 953-9)
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