MUSTARD COMPOUNDS
\mˈʌstəd kˈɒmpa͡ʊndz], \mˈʌstəd kˈɒmpaʊndz], \m_ˈʌ_s_t_ə_d k_ˈɒ_m_p_aʊ_n_d_z]\
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Strong alkylating and immunosuppressive agents whose biological activity is based on the presence of bis (2-chloroethyl)- groups. Although otherwise structurally diverse, the compounds have in common the capacity to contribute alkyl groups to DNA. They are generally highly toxic but include among their number many widely used and effective antineoplastic agents.
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Word of the day
EF 1H
- Peptide elongation factor 1 multisubunit protein that responsible GTP-dependent binding of aminoacyl-tRNAs eukaryotic ribosomes. alpha 1alpha) binds tRNA transfers it ribosome in a process linked to GTP hydrolysis. The beta and delta subunits (1beta, EF-1delta) are involved exchanging GDP for GTP. gamma subunit (1gamma) is structural component.