\mjˈʊɹəmˌɒnab sˌiːdˈiː θɹˈiː], \mjˈʊɹəmˌɒnab sˌiːdˈiː θɹˈiː], \m_j_ˈʊ_ɹ_ə_m_ˌɒ_n_a_b s_ˌiː_d_ˈiː θ_ɹ_ˈiː]\
Definitions of MUROMONAB CD3
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Anti-CD3 monoclonal antibody that exerts immunosuppressive effects by inducing peripheral T-cell depletion and modulation of the T-cell receptor complex (CD3/Ti). This biochemically purified IMMUNOGLOBULIN G is obtained through the fusion of mouse myeloma cells to lymphocytes from immunized animals to produce hybridomas that secrete specific antibodies to the T3 (CD3) antigens of human T-lymphocytes. It is often used as an immunosuppressive agent in transplantation.
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