MULTINUCLEATED GIANT CELLS
\mˌʌltɪnjˈuːklɪˌe͡ɪtɪd d͡ʒˈa͡ɪənt sˈɛlz], \mˌʌltɪnjˈuːklɪˌeɪtɪd dʒˈaɪənt sˈɛlz], \m_ˌʌ_l_t_ɪ_n_j_ˈuː_k_l_ɪ__ˌeɪ_t_ɪ_d dʒ_ˈaɪ_ə_n_t s_ˈɛ_l_z]\
Definitions of MULTINUCLEATED GIANT CELLS
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Multinucleated masses produced by the fusion of many cells; often associated with viral infections. In AIDS, they are induced when the envelope glycoprotein of the HIV virus binds to the CD4 antigen of uninfected neighboring T4 cells. The resulting syncytium leads to cell death and thus may account for the cytopathic effect of the virus.
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