MANUKOPF'S SIGN

\mˈanjuːkˌɒpfs sˈa͡ɪn], \mˈanjuːkˌɒpfs sˈa‍ɪn], \m_ˈa_n_j_uː_k_ˌɒ_p_f_s s_ˈaɪ_n]\

Definitions of MANUKOPF'S SIGN

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1898 - American pocket medical dictionary
By Willam Alexander Newman Dorland

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Procollagen Proline Dioxygenase

  • mixed-function oxygenase that catalyzes hydroxylation prolyl-glycyl-containing-peptide, usually in protocollagen, hydroxyprolylglycyl-peptide. The enzyme utilizes molecular oxygen with a concomitant oxidative decarboxylation of 2-oxoglutarate to succinate. EC 1.14.11.2.
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