MALIGNANT CARCINOID SYNDROME
\məlˈɪɡnənt kˈɑːsɪnˌɔ͡ɪd sˈɪndɹə͡ʊm], \məlˈɪɡnənt kˈɑːsɪnˌɔɪd sˈɪndɹəʊm], \m_ə_l_ˈɪ_ɡ_n_ə_n_t k_ˈɑː_s_ɪ_n_ˌɔɪ_d s_ˈɪ_n_d_ɹ_əʊ_m]\
Sort: Oldest first
-
A symptom complex associated with CARCINOID TUMOR and characterized by attacks of severe flushing of the skin, diarrheal watery stools, bronchoconstriction, sudden drops in blood pressure, edema, and ascites. The carcinoid tumors are usually located in the gastrointestinal tract and metastasize to the liver. Symptoms are caused by tumor secretion of serotonin, prostaglandins, and other biologically active substances. Cardiac manifestations constitute CARCINOID HEART DISEASE. (Dorland, 27th ed; Stedman, 25th ed)
By DataStellar Co., Ltd
Word of the day
Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.