MALIGNANT ASTROCYTOMA, OPTIC NERVE
\məlˈɪɡnənt ˌastɹəsɪtˈə͡ʊmə], \məlˈɪɡnənt ˌastɹəsɪtˈəʊmə], \m_ə_l_ˈɪ_ɡ_n_ə_n_t ˌa_s_t_ɹ_ə_s_ɪ_t_ˈəʊ_m_ə]\
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Glial cell derived tumors arising from the optic nerve, usually presenting in childhood. Roughly 50% are associated with NEUROFIBROMATOSIS 1. Clinical manifestations include decreased visual acuity; EXOPHTHALMOS; NYSTAGMUS; STRABISMUS; pallor or swelling of the optic disc; and INTRACRANIAL HYPERTENSION. The tumor may extend into the optic chiasm and hypothalamus. (Adams et al., Principles of Neurology, 6th ed, p681)
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tinctura quininae ammoniata
- A preparation made by dissolving quinin sulphate in alcohol [Br. Ph.].