MAKEHAM'S HYPOTHESIS

\mˈe͡ɪkhəmz ha͡ɪpˈɒθəsˌɪs], \mˈe‍ɪkhəmz ha‍ɪpˈɒθəsˌɪs], \m_ˈeɪ_k_h_ə_m_z h_aɪ_p_ˈɒ_θ_ə_s_ˌɪ_s]\

Definitions of MAKEHAM'S HYPOTHESIS

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Procollagen Proline Dioxygenase

  • mixed-function oxygenase that catalyzes hydroxylation prolyl-glycyl-containing-peptide, usually in protocollagen, hydroxyprolylglycyl-peptide. The enzyme utilizes molecular oxygen with a concomitant oxidative decarboxylation of 2-oxoglutarate to succinate. EC 1.14.11.2.
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