\mˈɑːlˈakɹabɪm], \mˈɑːlˈakɹabɪm], \m_ˈɑː_l_ˈa_k_ɹ_a_b_ɪ_m]\

Definitions of MAALE-AKRABBIM

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  • type multiple endocrine neoplasia characterized by virtually 100% incidence medullary thyroid carcinoma, a 50% pheochromocytoma, and lesser adenomas associated hyperparathyroidism. condition always transmitted through autosomal dominant inheritance. Genetic testing can identify individuals with the trait in early infancy. Treatment is usually excision of enlarged parathyroid glands. (From Holland et al., Cancer Medicine, 3d ed, pp1172-75)
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